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  • Title: Presence of colony promoting activity (CPA) in the supernatant of the long-term bone marrow cultures.
    Author: Tsurusawa M, Miyanomae T, Izumi H, Mori KJ.
    Journal: Leuk Res; 1983; 7(2):167-73. PubMed ID: 6602254.
    Abstract:
    Colony promoting activity (CPA) was detected in the supernatants of the bone marrow cell cultures. CPA itself had no granulocyte-macrophage colony stimulating activity (CSF); but did increase the number and the size of colonies induced by the optimal dose of CSF. This activity was dose dependent and not specific to CSF sources. CPA-responsive cells (target cells) were found in the bone marrow cell cultures as well as in the freshly isolated bone marrow.
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