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  • Title: Major hemorrhage and perforation due to a solitary cecal ulcer in a patient with end-stage renal failure.
    Author: Last MD, Lavery IC.
    Journal: Dis Colon Rectum; 1983 Aug; 26(8):495-8. PubMed ID: 6603343.
    Abstract:
    A case of solitary cecal ulcer with major hemorrhage followed by perforation after treatment with intra-arterial vasopressin in a patient with end-stage renal failure is presented. Though vasopressin has been used with success in the treatment of colonic hemorrhage, caution should be applied in patients with a bleeding cecal ulcer as the vasoconstriction produced by vasopressin may cause perforation in an area whose blood supply is already compromised.
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