These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Marked reduction of ANAE reactivity of T cells in the lymphoid tissues of monkeys treated with multiple high doses of human beta interferon.
    Author: Ohtaki S, Tatsumi M, Kohase M, Yamazaki S.
    Journal: Br J Exp Pathol; 1983 Dec; 64(6):638-43. PubMed ID: 6607063.
    Abstract:
    We report a histological study of the organs and tissues of cynomolgus monkeys which had received multiple high doses of human beta interferon (IFN). There were dense aggregations of small lymphocytes without the acid alpha-naphthyl acetate esterase (ANAE) reactivity in the thymus-dependent areas (TDA) of lymphoid tissues, indicating that the T mu cells of IFN-treated monkeys had lost this characteristic enzyme. This change of T mu cells in the tissues was not accompanied by a change in circulating T mu cells.
    [Abstract] [Full Text] [Related] [New Search]