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  • Title: Characterization of the effector cells in Con A-induced cytotoxicity against HEp 2 tumour targets.
    Author: Pócsik E, González-Cabello R, Benedek K, Perl A, Láng I, Gergely P.
    Journal: Acta Med Hung; 1983; 40(1):41-6. PubMed ID: 6607455.
    Abstract:
    Con A-induced cytotoxic activity of human lymphocyte subpopulations obtained by cell fractionation procedures was studied in a test system using human epipharynx carcinoma cells (HEp 2) as targets. Only T lymphocytes were cytotoxic, non-T cells exerted no cytotoxic activity, but enhanced the adherence of the tumour cells. Tnon-G lymphocytes (Fc-receptor negative T cells) were more active than TG cells (Fc-receptor-positive T cells) in mediating the Con A-induced cytotoxic reaction.
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