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  • Title: Interleukin 2 (IL2) is assigned to human chromosome 4.
    Author: Shows T, Eddy R, Haley L, Byers M, Henry M, Fujita T, Matsui H, Taniguchi T.
    Journal: Somat Cell Mol Genet; 1984 May; 10(3):315-8. PubMed ID: 6609441.
    Abstract:
    The human gene for interleukin 2 (IL2) was assigned to chromosome 4 using human-mouse somatic cell hybrids and Southern filter hybridization of cell hybrid DNA. To identify IL2, a recombinant DNA probe ( pIL2 - 50A ) was used which contained a human interleukin 2 cDNA insert which hybridized to a 3.5-kb fragment in human DNA when cleaved with the restriction enzyme EcoRI.
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