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  • Title: Chemistry and anti-inflammatory activity of 10-methylamino-11H-indeno[1,2-b]quinolin-11-one (MB 432) derivatives.
    Author: Bała M, Michańków M, Chojnacka-Wójcik E, Wiczyńska B, Tatarczyńska E.
    Journal: Pol J Pharmacol Pharm; 1983; 35(6):523-30. PubMed ID: 6610865.
    Abstract:
    The synthesis and properties of several derivatives of 10-methyl-amino- 11H -indeno[1,2-b] quinolin -11-one (MB 432) were described. New compounds were examined in carrageenin edema test in rats and writhing test in mice and compared to indomethacin and MB 432. The substitution in the rings of the indeno and quinoline parts deprived the compounds tested of a strong anti-inflammatory and analgesic properties characteristic of the parent system.
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