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  • Title: [Damage by gamma rays and heavy ions to superhelical structures of nuclear DNA].
    Author: Abel' Kh, Ertsgreber G, Langrok K.
    Journal: Radiobiologiia; 1983; 23(4):435-8. PubMed ID: 6611866.
    Abstract:
    Chinese hamster cells (V79-4), human lymphocytes and mouse ascites cell were exposed to gamma-rays and heavy ions (4He and 12C). Sedimentation of complexes containing DNA was studied after cell lysis by centrifugation in a neutral sucrose gradient. The distinctions noted after irradiation with gamma-rays and heavy ions are consistent with the idea of the superhelical organization of DNA into discrete and membrane-bound compact units. According to the estimates made the diameter of these complexes was approximately 0.2 micron and DNA content, about 2 X 10(9) dalton.
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