These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effect of polyunsaturated fatty acids in the diet on prostaglandin formation and the activity of the isolated heart].
    Author: Smirnov IE, Fatkhullin IA, Markov KhM.
    Journal: Vopr Pitan; 1983; (3):58-62. PubMed ID: 6613076.
    Abstract:
    Experiments on normotensive adult Wistar rats with hearts perfused according to the modified Langendorf technique and Okamoto-Aoki rats with a hereditary determined arterial hypertension kept on the diets with varying content of polyunsaturated acids (PUFA), series 6 and 3, have demonstrated that PUFA deficiency in the diet inhibited prostaglandin (PG) secretion by the heart of hypertensive rats, which was accompanied by the decreased rate of coronary perfusion. It has also been revealed that excess content of linoleic acid in lipid fractions of the diet was followed by an appreciable rise of prostacycline secretion, whereas the linoleic acid increase in the diet by the lowering of the overall amount of PG secreted by the heart of hypertensive rats and drop of the coronary perfusion rate. It has been demonstrated that these changes might be related to the modulations in the content of PUFA, PG precursors, in heart phospholipids.
    [Abstract] [Full Text] [Related] [New Search]