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  • Title: [Coagulation disorders in acute cranio-cerebral injuries].
    Author: Pfenninger E, Kilian J, Ahnefeld FW, Lindner K.
    Journal: Anasth Intensivther Notfallmed; 1983 Jun; 18(3):129-34. PubMed ID: 6614413.
    Abstract:
    Marked coagulation defects which have a very high mortality rate can arise following acute head injury. Damage to brain tissue leads to the release of substances promoting coagulation which can enter the vascular system and activate the enzyme cascade leading to clot formation. The more widespread cerebral damage is, the greater is the likelihood of clinically relevant DIC occurring. By carrying out clotting tests and taking therapeutic measures where necessary, a potentially lethal outcome can be avoided.
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