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Title: CNS lesions in neonatal isoimmune thrombocytopenia. Author: Naidu S, Messmore H, Caserta V, Fine M. Journal: Arch Neurol; 1983 Sep; 40(9):552-4. PubMed ID: 6615286. Abstract: We treated two siblings with classic neonatal isoimmune thrombocytopenia and porencephalic cysts in whom the CNS lesions occurred in a vascular distribution, for which there is no clear explanation. Whether the CNS vasculature is injured by the immune process at certain susceptible sites in larger vessels or whether there is a thrombotic process occurring at sites of vascular injury is speculative. This observation suggests that vascular factors are involved in the development of CNS lesions in this condition.[Abstract] [Full Text] [Related] [New Search]