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  • Title: Glycogenolysis in liver of phosphorylase kinase-deficient rats during liver perfusion and ischaemia.
    Author: Lutaya G, Sharma RJ, Griffiths JR.
    Journal: Biochem J; 1983 Aug 15; 214(2):645-8. PubMed ID: 6615485.
    Abstract:
    Liver glycogen degradation and phosphorylase activity were measured in normal and phosphorylase kinase-deficient (gsd/gsd) rats. During perfusion or ischaemia, gsd/gsd-rat livers showed a brisk glycogenolysis. There was also a small (1.9-fold) but significant transient increase in their phosphorylase alpha activity during ischaemia, despite their phosphorylase b kinase deficiency; it seems unlikely, however, that this was the main determinant of the glycogenolysis.
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