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  • Title: [Changes in oxygen tension in the cerebral cortex during hemodilution].
    Author: Stolbov AL.
    Journal: Biull Eksp Biol Med; 1983 Sep; 96(9):18-20. PubMed ID: 6616045.
    Abstract:
    Wistar rats were subjected to gradual blood replacement with 7% albumin (hemodilution). Hematocrit and mean arterial pressure were measured periodically. Polarographic platinum microelectrodes with a tip 3-8 microns in diameter were used to study variation of oxygen tension (pO2) in the brain cortex during hemodilution. Some areas showed a significant decrease in the brain pO2 after hematocrit dropped to 30%. In animals with an initially low pO2 (13.1 +/- 1.7 mm Hg), this parameter decreased more slowly than in rats with a higher basic pO2 (24.5 +/- 1.7 mm Hg).
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