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Title: Synthesis of some 2- and 4-methoxyacetylaminobenzenesulphonylamino acid derivatives and their antimicrobial activity. Author: El-Naggar AM, El-Haddad AF, El-Ghaffar SA, Elsayed RA. Journal: Farmaco Sci; 1983 Jul; 38(7):488-97. PubMed ID: 6617848. Abstract: The synthesis of a series of 3-acetylamino-4-methoxy-,2-acetylamino-4-methoxy- and 2-methoxy-5-acetylaminobenzenesulphonylamino acids, methyl esters, hydrazides and dipeptide methyl esters (IV-LXI) is described. Some o-, m- and p-anisidine and 2-aminopyridine derivatives have also been prepared by analogous procedure. Twenty of various by substituted acetylaminomethoxybenzenesulphonylamino acid and dipeptide derivatives were found to possess specific antimicrobial activities towards different microorganisms.[Abstract] [Full Text] [Related] [New Search]