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  • Title: Azaprostaglandins. Synthesis and antiulcer activity of 11-deoxy-8-azaprostaglandin analogues.
    Author: Baraldi PG, Simoni D, Casolari A, Manfredini S.
    Journal: Farmaco Sci; 1983 Jul; 38(7):498-507. PubMed ID: 6617849.
    Abstract:
    We describe the synthesis and the antiulcer activity of new 11-deoxy-8-aza-PGE1 analogues (III a) and its C15-epimer (III b), (IV a) and its C15-epimer (IV b), featured by a triple bond in place of the C13-C14 trans double bond and a 16,16-dimethyl-17-oxabutyl omega-chain, respectively.
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