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  • Title: Evidence for dopamine-containing renal nerves.
    Author: Dinerstein RJ, Jones RT, Goldberg LI.
    Journal: Fed Proc; 1983 Oct; 42(13):3005-8. PubMed ID: 6617896.
    Abstract:
    The existence of the specific renal DA1 postsynaptic receptor for dopamine (DA) has prompted the search for a counterpart dopaminergic innervation. In the canine kidney there is an increased proportion of DA as a percentage of norepinephrine (NE), and both NE and DA are lost after chronic denervation. In the rat and dog, renal stimulation increases the net secretion of both NE and DA; renal denervation eliminates NE but only partially reduces DA secretion. Histological techniques have identified DA-containing neuronal elements in the kidney. Thus there is growing evidence for a prejunctional dopaminergic counterpart to the DA1 receptor.
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