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  • Title: [Fundamental and clinical studies on T-1982 (cefbuperazone) in the field of obstetrics and gynecology].
    Author: Yamamoto T, Yasuda J, Okada H, Kanao M.
    Journal: Jpn J Antibiot; 1983 May; 36(5):1010-7. PubMed ID: 6620552.
    Abstract:
    Fundamental and clinical studies were carried out on T-1982 (cefbuperazone) a new cephamycin antibiotic, with the following result. Following a single intravenous administration of 1.0 g of T-1982, the transfer of T-1982 to the internal genital organs was found to be good. The transfer of T-1982 to retroperitoneal fluid was also good. In clinical trial, T-1982 was administered to 10 patients with obstetrical and gynecological infection. Efficacy was excellent in 4 cases and good in 6 cases. No side effects were observed. In laboratory findings, a transient elevation of alkaline phosphatase was noted in 1 case.
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