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  • Title: Interaction between manganese and phenobarbital on hexobarbital hypnosis in the male rat.
    Author: Deimling MJ, Schnell RC.
    Journal: Res Commun Chem Pathol Pharmacol; 1983 Jul; 41(1):165-8. PubMed ID: 6622829.
    Abstract:
    Pretreatment of male rats with phenobarbital markedly decreases while treatment with manganese prolongs the duration of hexobarbital hypnosis in male rats. When both agents were administered simultaneously, the manganese-induced prolongation of hexobarbital was prevented.
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