These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Differences in K+-induced relaxation of canine femoral and renal arteries.
    Author: Bukoski RD, Seidel CL, Allen JC.
    Journal: Am J Physiol; 1983 Oct; 245(4):H598-603. PubMed ID: 6624928.
    Abstract:
    The extent and initial rate of potassium-induced relaxation of canine femoral and renal arteries were measured as a function of potassium concentration [K+]. Both parameters were greater in the renal artery at low [K+]; the dissociation constant for potassium of the femoral artery was greater than that of the renal artery. If potassium-induced relaxation reflects sodium pump activity, then these data indicate that the sodium pumps of the two arteries are different. When we repeated the above experiments in a lowered sodium medium, the rate and extent of potassium-induced relaxation and the apparent affinity for potassium increased in the femoral artery as predicted by kinetic models based on both isolated Na+-K+-ATPase and intact tissue. The same parameters in the renal artery, however, were unaffected by lowered sodium. These results and those presented in the companion paper [Am. J. Physiol. 245 (Heart Circ. Physiol. 14): H604-H609, 1983] can be interpreted to mean that potassium-induced relaxation does not accurately reflect sodium pump function in canine renal arteries.
    [Abstract] [Full Text] [Related] [New Search]