These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effect of a bioflavinoid (4-methylesculetin) on the response of calf hepatic arteries to serotonin in the presence of indomethacin].
    Author: Bettini V, Gamba G, Guido A, Legrenzi E, Mayellaro F.
    Journal: Boll Soc Ital Biol Sper; 1983 Sep 30; 59(9):1231-5. PubMed ID: 6626355.
    Abstract:
    The aim of this work is to study the mechanism by which 4-methylsculetin (4-Me) inhibits the serotonin induced contraction in smooth muscle. The effect of 4-Me, alone or associated with ascorbic acid, on basal tone and serotonin induced contraction of isolated hepatic artery strips have been studied. Experiments have been carried out in the presence of indomethacin (IN), specific inhibitor of prostaglandin-synthetase. IN suppressed the depressive effect of 4-Me on the serotonin dependent contraction. Therefore, it seems reasonable to conclude that the 4-Me influence could be mediated by prostaglandins release smooth muscle.
    [Abstract] [Full Text] [Related] [New Search]