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  • Title: Hemoglobin Maputo: a new beta-chain variant (alpha 2 beta 2 47 (CD6) Asp replaced by Tyr) in combination with hemoglobin S, identified by high performance liquid chromatography (HPLC).
    Author: Marinucci M, Boissel JP, Massa A, Wajcman H, Tentori L, Labie D.
    Journal: Hemoglobin; 1983; 7(5):423-33. PubMed ID: 6629824.
    Abstract:
    During a routine hematological investigation, a slowly-moving hemoglobin variant was detected in a 2-year-old child from Maputo (Mozambique) in combination with hemoglobin S. Structural studies carried out by HPLC demonstrated a previously unreported amino acid substitution, beta 47 (CD6) Asp replaced by Tyr. The new hemoglobin variant has been named hemoglobin Maputo.
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