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  • Title: The influence of beta blockers on cardiovascular reactivity and Type A behavior pattern in hypertensives.
    Author: Schmieder R, Friedrich G, Neus H, Rüdel H, von Eiff AW.
    Journal: Psychosom Med; 1983 Oct; 45(5):417-23. PubMed ID: 6635104.
    Abstract:
    The influence of beta blockers on Type A behavior pattern and cardiovascular reactivity was tested. Nineteen white, male hypertensive patients were divided at random into two therapeutic groups (100 mg atenolol versus 50 mg hydrochlorothiazide + 5 mg amiloride (control group) ). For each patient, the German version of the structured interview was performed before therapy and at a minimum of 4 weeks after normalization of clinical resting casual blood pressure (BP). Prior to therapy, there were no differences in age, BP at rest, cardiovascular reactivity, and Type A between the two groups. After therapy, the patients treated with beta blockers changed Type A characteristics toward Type B, regardless where they started on the Type A scale, and beta blockers attenuated cardiovascular reactivity. In this study, Type A (hypertensive patients) was not associated with greater cardiovascular reactivity.
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