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  • Title: [Interrelations between adenine nucleotides in Penicillium nigicans Thom].
    Author: Rogal' IG.
    Journal: Antibiotiki; 1983 Sep; 28(9):650-2. PubMed ID: 6638978.
    Abstract:
    Based on the participation of ATP in biosynthesis of NAD and NADP the correlation coefficients were calculated between the levels of ATP, ADP, NAD and NADP, as well as between the concentration ratios of ATP/ADP and NADP in the mycelium of P. nigricans. The data of the previous studies on the concentration of these nucleotides in the mycelium of cultures subjected to periodical feeding of glucose, NaNO3 or their mixtures on the 5th-7th days of the organism development were used. No relation between the levels of ATP and NAD or NADP and the ratios of ATP/ADP and NAD was observed in any of the variants. Feeding of NaNO3 allowed disclosing the relation between the concentrations of ADP and NAD, while feeding of the NaNO3 mixture with glucose allowed the relation between ADP and NADP and negative relation between the ratio of ATP/ADP and NADP to be ascertained. Relation between the levels of NAD and NADP was observed in all the variants, including the control ones. The mechanism of the effect of NaNO3 and its role in revealing the relations between the nucleotide levels are discussed.
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