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  • Title: Long-term follow-up of patients receiving aprindine. Safety and efficacy.
    Author: Strasberg B, Prechel D, Bauman J, Coelho A, Swiryn S, Bauernfeind R, Rosen KM.
    Journal: Arch Intern Med; 1983 Nov; 143(11):2131-3. PubMed ID: 6639232.
    Abstract:
    Aprindine hydrochloride is an antiarrhythmic agent presently undergoing clinical trials in the United States. Because of the narrow therapeutic-toxic ratio observed for aprindine, the long-term follow-up of these patients is important in determining the potential clinical effectiveness of this drug. In this report we examine our experience with 30 patients with drug-resistant arrhythmias who were discharged receiving aprindine and who were followed up for a mean period of 25 months.
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