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  • Title: [Formation of some enzymic systems in the human fetal brain during development].
    Author: Drel' KA, Skorobogataia TG, Chernenkova MP, Borzenko VG.
    Journal: Ukr Biokhim Zh (1978); 1978; 50(2):167-70. PubMed ID: 664028.
    Abstract:
    The data of studies in the monoaminoxidase, nuclease and transaminase activity in fractions of mitochondria and nuclei of the human fetus brain in the process of the fetus development evidence for the changes in the activity depending on the morphological and functional maturation of the organ during the antenatal ontogenesis. The monoaminoxidase activity increases by the time of birth. By the 40th week of development the activity of glutamic-aspartic transaminase increases as well. The activity of glutamic-alanine transaminase changes insignificantly. A considerable decrease in the activity of DNase and RNase in the mentioned fractions is observed by the time of the fetus birth. The maximal activity of these enzymes is observed in the first half of the fetus intrauterine development.
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