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  • Title: Effect of prolonged inhibition of histidine decarboxylase on tissue histamine concentrations.
    Author: Bouclier M, Jung MJ, Gerhart F.
    Journal: Experientia; 1983 Nov 15; 39(11):1303-5. PubMed ID: 6641910.
    Abstract:
    In rats, chronic infusion of alpha-fluoromethyl histidine, a selective irreversible inhibitor of mammalian histidine decarboxylase, caused a marked depletion of histamine in all tissues examined. There were no gross pharmacological effects associated with this depletion.
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