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  • Title: [Inhibition of bone tissue formation by propane-2,2-diphosphonate].
    Author: Menge M.
    Journal: Fortschr Med; 1983 Oct 20; 101(39):1787-91. PubMed ID: 6642385.
    Abstract:
    Among other diphosphonates here described propane-2,2-diphosphonate displays specific effects on bone-turnover. In contrast to other diphosphonates propane-2,2-diphosphonate inhibits especially different enzymes of growing bone and therefore inhibits formation of bone. The indication for the clinical use follows from that effect: pathologic states with increased bone formation may be treated by application of propane-2,2-diphosphonate.
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