These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Thickening of the human dorsal root ganglion perineurial cell basement membrane in diabetes mellitus.
    Author: Johnson PC.
    Journal: Muscle Nerve; 1983 Oct; 6(8):561-5. PubMed ID: 6646159.
    Abstract:
    Lumbar dorsal root ganglia were sampled at autopsy from 27 diabetics and 22 nondiabetics. Using quantitative ultrastructural morphometry, the perineurial cell basement membrane thickness was estimated for each case, and a highly significant difference was found between the patient means for each group (nondiabetics 114 +/- 18 nm vs. diabetics 203 +/- 64 nm, P less than 0.001). These results indicate that perineurial cell basement membrane thickening probably is present diffusely throughout the diabetic peripheral nervous system because it has been reported in the sural nerves and dermal nerves. The increased permeability of the blood-nerve barrier of the dorsal root ganglia is apparently not a factor in the development of this basement membrane hypertrophy.
    [Abstract] [Full Text] [Related] [New Search]