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  • Title: Ultrastructural changes of hepatocyte organelles induced by chemicals and their relation to fat accumulation in the liver.
    Author: Mori M.
    Journal: Acta Pathol Jpn; 1983 Sep; 33(5):911-22. PubMed ID: 6650171.
    Abstract:
    Fatty liver was induced in the rats shortly after administration of cycloheximide, ethionine, orotic acid, monensin or colchicine. It was strongly suggested that derangements in one or more of the hepatic lipoprotein metabolic steps, which occur at the levels of endoplasmic reticulum, Golgi apparatus and secretory vacuoles lead to an accumulation of triglyceride within hepatocytes.
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