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  • Title: Efficacy of a benzenedisulfonamide against experimental Fasciola hepatica infections in calves.
    Author: Wyckoff JH, Bradley RE.
    Journal: Am J Vet Res; 1983 Nov; 44(11):2203-4. PubMed ID: 6650967.
    Abstract:
    The anthelmintic efficacy of a benzenedisulfonamide was evaluated by administering the drug parenterally at dosage levels of 2, 4, 8, and 16 mg/kg of body weight to crossbred Brahman calves with experimental Fasciola hepatica infections. In the 3-week period after treatment, fluke ova counts of treated calves were markedly reduced from counts obtained just before treatment. At necropsy, the mean fluke recovery for all 4 benzenedisulfonamide dosages were significantly (P less than 0.01) reduced. The efficacy of benzenedisulfonamide against F hepatica at dosage levels of 2, 4, 8, and 16 mg/kg was 97.5%, 99.5%, 100%, and 100%, respectively.
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