These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


PUBMED FOR HANDHELDS

Search MEDLINE/PubMed


  • Title: Long-term clorgyline treatment antagonizes the eating and motor function responses to m-chlorophenylpiperazine.
    Author: Cohen RM, Aulakh CS, Murphy DL.
    Journal: Eur J Pharmacol; 1983 Oct 14; 94(1-2):175-9. PubMed ID: 6653658.
    Abstract:
    Treatment for 21 days but not 3 days with clorgyline, a selective monoamine oxidase type A inhibitor with antidepressant effects, causes significant escape from m-chlorophenylpiperazine's effects on food intake, sedation level and induction of limb movements, but sensitizes rats to ejaculation. These findings support the prior reports of functional serotonin pathway adaptational changes in the motor system in response to antidepressant treatment and extend these findings to serotonin pathways involved in eating behavior.
    [Abstract] [Full Text] [Related] [New Search]