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  • Title: [Mechanism of the vasodilator action of kavinton on the cerebral vessels].
    Author: Plotnikov MB, Kotov AN.
    Journal: Farmakol Toksikol; 1983; 46(6):36-9. PubMed ID: 6653756.
    Abstract:
    Experiments on human middle cerebral and cat internal maxillary arteries have shown high vasodilative activity of cavinton. The mechanism of the vasodilative action of the drug involves inhibition of the ingress of exocellular calcium via electrogenic and chemosensitive channels, suppression of calcium mobilization from the intracellular depot with depolarization of the membranes of vascular smooth cells and a decrease in phosphodiesterase activity.
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