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  • Title: [Functional relations between the adrenal cortex, thyroid gland and pineal body. I. Reactions of the adrenal cortex following interference with the thyroid regulatory cycle].
    Author: Peschke E, Schumann J, Schrank F.
    Journal: Gegenbaurs Morphol Jahrb; 1983; 129(5):599-624. PubMed ID: 6654001.
    Abstract:
    Histologic-cytological and morphometrical changes were investigated in the adrenal cortex of male Wistar-rats in experimental hypo- and hyperthyroid situation. Under hypothyroid metabolism's situation (methylthiouracil-application or thyroidectomy) a regressive transformation was found: It is a decrease of secretion of the fascicular zone. The glomerular zone was activated. After long-time application of high dosis of thyroxin, the histological findings show some criteria of an increasing function and also of a beginning exhaustion, too. It is evident, that the duration of the hyperthyroid situation is important. Thyroxin is an unspecific stressor. The long-time application of high thyroxin dosis induced a regressive transformation and atrophic changes in the adrenal cortex. The nuclei of the fascicular and the glomerular zone were diminuated significantly.
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