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  • Title: Pathogenesis of Legg-Calvé-Perthes disease.
    Author: Perugia L, Ippolito E.
    Journal: Ital J Orthop Traumatol; 1983 Jun; 9(2):211-7. PubMed ID: 6654656.
    Abstract:
    After reviewing the most widely accredited theories on pathogenesis advanced up to now, the authors report the results of a histological histochemical and ultrastructural study of the upper femoral epiphysis in Legg-Calvé-Perthes disease. They conclude that the primary lesion is probably a dysplastic change in the epiphyseal cartilage.
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