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  • Title: The haemoglobin pattern of sickle cell and haemoglobin C beta +-thalassaemia in Liberia.
    Author: Willcox M.
    Journal: J Med Genet; 1983 Dec; 20(6):430-2. PubMed ID: 6655669.
    Abstract:
    Haemoglobin components in 21 Liberians with Hb S beta +-thalassaemia and four with Hb C beta +-thalassaemia were measured to classify the forms of beta +-thalassaemia present in the population. In 20 Hb S and all Hb C beta +-thalassaemics the data were consistent with the interaction of these variants with the mild type 2 (Negro) form of beta +-thalassaemia. The data available were insufficient to classify the remaining case, a young child. It was concluded that the clinically more severe type of beta +-thalassaemia giving Hb A levels of 5 to 15% in compound heterozygotes is probably uncommon in Liberia.
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