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  • Title: Effect of granulocytic chalone on acute myeloid leukaemia in man. A follow-up study.
    Author: Vilpo JA, Levanto A, Jones WA.
    Journal: Lancet; 1977 Apr 09; 1(8015):771-4. PubMed ID: 66569.
    Abstract:
    Non-pyrogenic preparations of granulocytic chalone have been administered to patient with acute myeloid leukaemia (A.M.L.) who had relapsed after chalone-induced complete remission of the disease. Another regression of the leukaemia was obtained. Normal and leukaemic granulocytes were inhibited without effect on other cell types. Survival was prolonged in 4 other patients with A.M.L. Further investigations are needed to elucidate the therapeutic role of granulocytic chalone.
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