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  • Title: [Molecular mechanisms of radiation death of lymphoid cells. Protein poly-ADP-ribosylation in thymocyte fractions].
    Author: Sorokina NI, Spiridonov MA, Filippovich IV, Romantsev EF.
    Journal: Radiobiologiia; 1983; 23(6):739-42. PubMed ID: 6657932.
    Abstract:
    A study was made of the process of poly-ADP-ribosylation of proteins in cells of radioresistant and radiosensitive fractions of mouse thymus lymphocytes after irradiation of isolated cells with a dose of 25 Gy. It was shown that activation of ADP-ribosylation of proteins occurred simultaneously with the formation of single-strand DNA breaks in thymocytes, and the degree of activation in radioresistant and radiosensitive fractions was nearly the same.
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