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  • Title: [Prevention of cardiac contractile function disorders during prolonged stress by preliminary adaptation to short-term stress exposure].
    Author: Meerson FZ, Katkova LS, Kozlov IuP, Manukhina EB.
    Journal: Biull Eksp Biol Med; 1983 Dec; 96(12):25-8. PubMed ID: 6661542.
    Abstract:
    Studies of contractile function of an isolated right auricle in Wistar rats have demonstrated that long-term immobilization stress (fixation in the lying position for 6 h) results in the decreased extensibility of the auricle and pronounced depression of the developed tension. Preliminary adaptation of the animals to short-term immobilization stress (daily fixation in the lying position for 1 h over 10 days) per se insignificantly affects the extensibility and contractile function of the auricle but in effect it reduces its adrenoreactivity and completely prevents the post-stressor rigidity of the auricle and its function abnormality after long-term stress.
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