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  • Title: Isotype-specific measurement of rheumatoid factor with reference to clinical features of rheumatoid arthritis.
    Author: Tarkowski A, Nilsson LA.
    Journal: J Clin Lab Immunol; 1983 Nov; 12(3):129-35. PubMed ID: 6663605.
    Abstract:
    Serum levels of IgG, IgA and IgM rheumatoid factor (IgG RF, IgA RF and IgM RF) were estimated by means of the diffusion-in-gel enzyme-linked immunosorbent assay (DIG-ELISA), in 90 Waaler-Rose positive and Waaler-Rose negative rheumatoid arthritis (RA) patients as well as in 60 controls. The presence of IgG and/or IgA RF was shown to be of high predictive value concerning the occurrence of systemic manifestations in RA. All RF isotypes measured were good indicators of the disease activity.
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