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  • Title: [Autopsy case of atypical medulloblastoma in an adult].
    Author: Nakamura T, Matsubara O, Miyazaki M, Kasuga T, Kamiyama R, Nakamura T, Fujimoto T, Inaba Y.
    Journal: Gan No Rinsho; 1983 Nov; 29(14):1651-6. PubMed ID: 6663712.
    Abstract:
    A 24-year-old female complained of headache and vomiting. The brain-CT scan demonstrated a tumor shadow in the right cerebellar hemisphere. The tumor was partially resected, and irradiation therapy was started. She died of intraventricular hemorrhage about 6 months after the onset of symptoms. Autopsy revealed a recurrent tumor mass in the cerebellum extending to the brain stem. It showed systemic metastases to the leptomeninx, liver, bones and ovaries. Histological examination showed a tumor which was a primarily composed of typical medulloblastoma cells with occasional Homer-Wright type rosettes. It partly showed glioblastoma-like configuration. Some tumor cells were positive for GFAP by the PAP method, suggesting glial differentiation.
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