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  • Title: [Coordinated regulation of the enzyme activity of glucose transport and metabolism in Brevibacterium flavum].
    Author: Ruklish MP, Labane LIa, Viestur UE, Shvinka IuE, Shmite IA.
    Journal: Mikrobiologiia; 1983; 52(5):739-43. PubMed ID: 6664311.
    Abstract:
    A coordination was established between the rate of glucose transport and the activity of enzymes involved in glycolysis and the citric acid cycle (CAC) in Brevibacterium flavum cells producing lysine: the rate of glucose transport and the activity of enzymes catalysing glycolysis increased when the activity of CAC enzymes decreased and vice versa. The activity of glycolytic enzymes and the rate of glucose transport in the cells increased also when electron transport through the respiration chain was inhibited and when oxidation and phosphorylation in the respiration chain were uncoupled. The rate of ATP synthesis in the cells is presumed to coordinate the rate of glucose transport and the activity of glycolytic and CAC enzymes in the cells.
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