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  • Title: Are the high mobility group non-histone chromosomal proteins associated with 'active' chromatin?
    Author: Goodwin GH, Johns EW.
    Journal: Biochim Biophys Acta; 1978 Jun 22; 519(1):279-84. PubMed ID: 667067.
    Abstract:
    When 10--20% of the DNA in thymus and liver nuclei is rendered acid-soluble by DNAase I digestion, under conditions which may be expected to specifically degrade away most of the transcribed sequences, very little of the high-mobility-group non-histone proteins are released from the nuclei. Therefore, high-mobility-group proteins are probably not specifically associated with this portion of the genome.
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