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  • Title: Role of phosphatidylcholine on microsomal chain elongation and the fate of stearoyl-CoA in rat liver microsomes.
    Author: Kawashima Y, Suzuki Y.
    Journal: Biochim Biophys Acta; 1978 Jun 23; 529(3):489-92. PubMed ID: 667088.
    Abstract:
    The effect of phosphatidylcholine dispersion on the chain elongation of palmitoyl-CoA in rat liver microsomes has been investigated. Addition of phosphatidylcholine increased the formation of stearic acid and its incorporation into phosphatidylcholine. In the presence or absence of phosphatidylcholine, newly-formed stearic acid was preferentially incorporated into the C-1 position of phosphatidylcholine. The incorporation of newly formed stearic acid into microsomes was much higher than that into the added phosphatidylcholine dispersion.
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