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  • Title: [Sclerocornea. Ultrastructural and morphologic study].
    Author: Petroutsos G, Patey A, Savoldelli M, Pouliquen Y.
    Journal: J Fr Ophtalmol; 1983; 6(10):769-75. PubMed ID: 6672052.
    Abstract:
    A 6 month old white male infant had bilateral congenital diffuse sclerocornea. A penetrating keratoplasty was performed in his left eye. Histologic examination by electron microscopy demonstrated: the presence of vacuoles in the superficial epithelial layer, the absence of Bowman's membrane, a disorganization of collagen fibers and lamellae more prominent in the middle stroma, and an extremely thin Descemet's membrane. A comparison, using an automatized image analysis method, was carried out between the stroma of sclerocornea and a normal cornea. Morphometric analysis of the collagenous fibril's diameter and the interfibrillar distances demonstrated a statistically significant difference (p less than 0.001) between the two corneas examined.
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