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  • Title: Prostaglandins released into human burn blister fluid.
    Author: Sugiyama S, Norimatsu I, Kobayashi M, Ozawa T, Aoyama H, Suzuki K, Izawa Y.
    Journal: Biomedicine; 1978 Apr; 29(2):51-3. PubMed ID: 667287.
    Abstract:
    Acidic lipids were isolated from human burn blister fluid and the presence of prostaglandins E and F compounds was demonstrated by the thin-layer chromatography. Prostaglandins E1, E2 and F2alpha were identified and quantitatively determined by radioimmunoassay and by gas-liquid chromatography/mass spectrometry. Analyses on burn blister fluid obtained from 35 patients with skin burn indicated an extensive release of prostaglandins into the blister after burn injury in a few hours. The high levels of prostaglandins in burn blister fluid decreased gradually during 24 hours after burn.
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