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  • Title: Caffeine contracture and iodoacetate rigor in frog skeletal muscle. A comparison.
    Author: Schwarz RP, Hsieh R, Johnson WH.
    Journal: Biophys J; 1978 Jun; 22(3):501-6. PubMed ID: 667298.
    Abstract:
    Frog sartorius muscle treated with 5.0 mM or greater caffeine exhibits stiffness similar to that obtained from muscle in iodoacetate rigor. The data provide quantitative evidence that suggests that caffeine at irreversible contracture-producing concentrations somehow induces a rigor or rigorlike state in skeletal muscle.
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