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  • Title: Sister chromatid exchange in patients affected by severe psoriasis.
    Author: Crippa L, Gilardi S, Assimacopoulos A, Engel E.
    Journal: J Genet Hum; 1983 Dec; 31 Suppl 5():377-84. PubMed ID: 6674413.
    Abstract:
    An analysis of the sister chromatid exchanges has been carried out in lymphocytes from patients suffering from a severe form of psoriasis--pustular psoriasis (von Zumbusch), eruptive psoriasis vulgaris (more than 30% of the skin surface), severe arthropathic psoriasis and psoriatic erythroderma. These patients had never received treatment for their disorder. Our results, which show a normal level of sister chromatid exchanges in their blood cells, argue against the presence of a mutagenic factor in such patients.
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