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  • Title: [Platelet aggregation and platelet and plasma fatty acid levels in the child with migraine. Apropos of 40 case reports].
    Author: Derambure S, Bouchet P, Sezille G, Moulin S, Parquet A, Lelong M.
    Journal: Pediatrie; 1983 Dec; 38(8):523-31. PubMed ID: 6674921.
    Abstract:
    The authors have studied platelet aggregability in the presence of ADP and collagen in a population of 40 migrainous children between migraine attacks. They completed their investigations by a qualitative dosage in platelets and in plasma of fatty acids, precursors of prostaglandins, which are well known for their importance in platelet aggregation and vasculomotor reactions. This study was made in comparison with an equal number of controls chosen from the same age-groups. The authors didn't find the hyperaggregability observed by other authors in grown-up populations. They noticed a light-but statistically significant-diminution of linoleic acid in the platelets and in the plasma. A study based on observations does not entirely confirm for certain an alimentary origin.
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