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  • Title: Mucoepidermoid carcinoma of the palpebral mucocutaneous junction. A clinical, light microscopic and electron microscopic study of an unusual tubular variant.
    Author: Herschorn BJ, Jakobiec FA, Hornblass A, Iwamoto T, Harrison WG.
    Journal: Ophthalmology; 1983 Dec; 90(12):1437-46. PubMed ID: 6677843.
    Abstract:
    An 81-year-old man developed a left lower lid lesion. The lid margin was red, thickened, and indurated with foci of ulceration and telangiectasia on the palpebral conjunctiva. The initial clinical impression was either a chalazion or sebaceous carcinoma, and an incisional biopsy was performed. By light and electron microscopy, the tumor demonstrated infiltrating cords of cells with an admixture of epidermoid and mucus-secreting elements arranged in a distinctive elongated tubular fashion. The involved lid was resected and reconstructed by a Hughes' tarso-conjunctival graft with marsupialization of the canaliculus. No recurrence has been encountered after a year. Mucoepidermoid carcinoma of the conjunctiva is a rare, locally aggressive neoplasm characterized in all seven previously reported cases by recurrence within 6 months, and a high incidence of intraocular or orbital invasion.
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