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  • Title: Combined effects of cholestyramine and probucol on regression of atherosclerosis in rhesus monkey aortas.
    Author: Wissler RW, Vesselinovitch D.
    Journal: Appl Pathol; 1983; 1(2):89-96. PubMed ID: 6678159.
    Abstract:
    Adult male rhesus monkeys were fed a high fat, high cholesterol diet for 13 months. During the subsequent 12 months this diet was continued, but the animals were also treated with cholestyramine and/or probucol. The combined drug treatment caused lowering of blood cholesterol without a change in HDL-cholesterol. Regression of plaques was more marked than in animals treated with either drug alone. Animals remained in good health during the treatment period.
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