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  • Title: Inhibition of adenylate cyclase by a membrane protein from rat cerebrum.
    Author: Sano M, Kitajima S, Mizutani A.
    Journal: Brain Res; 1983 Mar 28; 264(1):157-9. PubMed ID: 6682691.
    Abstract:
    The inhibitor protein of adenylate cyclase was partially purified from detergent-extract of rat brain. The inhibition occurred without lag phase. Calmodulin, GTP, guanyl 5'-yl imidodiphosphate (Gpp (NH) p) and forskolin did not change the inhibition, but activities stimulated by NaF or Mn2+ were more resistant for the inhibition. The inhibitor might include an essential sulfhydryl group.
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